According to Medical News Today, a new study had been done regarding growths in the brain with mice. These creatures have been utilized in brain tumor research efforts before, of course, and some of the finest results have come to the surface. When there are efforts seen amongst these mice, it is very likely that humans will be able to benefit from them in some way or another. I believe this to be the case after reading up on the results that came from this particular study.
The article talked about how those within the John Hopkins University School of Medicine have been able to bring this drug into great effect. For those of you not in the know, 5-azacytidine may be able to prove useful in the realm of brain tumor research. You have to keep in mind that it had a previous effect on pre-leukemia in the past. It has since been utilized in this study, which should be focused on by organizations such as Voices against Brain Cancer.
Gliomas - seen as the most common and rapidly growing tumors in the brain - are going to be helped thanks to this drug. In particular, the drug will be able to target the mutation referred to simply as IDH1. For those of you who are unfamiliar with what exactly this entails, it is an alteration that is seen in 70 to 80 percent of all lower-grade tumors in patient. This mutation will make it impossible for the body to utilize protein for the sake of transitioning glucose into energy.
That way that 5-azacytidine was administered was through mice, which was done during a period of 14 weeks. What was seen by the end of the process was that tumor growth had been reduced tremendously and a relapse had not been seen as well. After drug administration had been halted, tumors did not come back after 7 weeks. Tumors have a tough time regressing with certain treatments but that is what the case was in this regard and it is beneficial, to put it lightly.
It's apparent that tumor regression is not going to be very common but it has been seen here. As a result, I have to believe that brain tumor research is only going to be made that much better. Is it possible that future studies will come about? I have to believe that this will be the case but, to me, it's just a matter of the finest researchers changing what has been done with the mice and shifting the results so that they will be able to help humans in the same way.
The article talked about how those within the John Hopkins University School of Medicine have been able to bring this drug into great effect. For those of you not in the know, 5-azacytidine may be able to prove useful in the realm of brain tumor research. You have to keep in mind that it had a previous effect on pre-leukemia in the past. It has since been utilized in this study, which should be focused on by organizations such as Voices against Brain Cancer.
Gliomas - seen as the most common and rapidly growing tumors in the brain - are going to be helped thanks to this drug. In particular, the drug will be able to target the mutation referred to simply as IDH1. For those of you who are unfamiliar with what exactly this entails, it is an alteration that is seen in 70 to 80 percent of all lower-grade tumors in patient. This mutation will make it impossible for the body to utilize protein for the sake of transitioning glucose into energy.
That way that 5-azacytidine was administered was through mice, which was done during a period of 14 weeks. What was seen by the end of the process was that tumor growth had been reduced tremendously and a relapse had not been seen as well. After drug administration had been halted, tumors did not come back after 7 weeks. Tumors have a tough time regressing with certain treatments but that is what the case was in this regard and it is beneficial, to put it lightly.
It's apparent that tumor regression is not going to be very common but it has been seen here. As a result, I have to believe that brain tumor research is only going to be made that much better. Is it possible that future studies will come about? I have to believe that this will be the case but, to me, it's just a matter of the finest researchers changing what has been done with the mice and shifting the results so that they will be able to help humans in the same way.
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