Tuesday, November 26, 2013

Gene Mutations Within Glioblastoma Research

By Rob Sutter


Those who have been involved in glioblastoma research will be able to tell you about this condition in particular. For those who don't know, gliomas are seen as not only the most prevalent types of tumors in the brain but the most aggressive, to boot. It's clear that there is more that can be done to help this way of research but what will it entail? It seems as though there should be work done regarding various gene mutations and particular relations that will be seen along with them.

BioNews Texas put together an article in reference to the various findings that have been connected to the field of glioblastoma multiforme. The report stated that, in 2013, there is an expected statistic of 23,000 cases of this condition to be seen. In addition, there seems to be a 15-month diagnosis for each new patient .Taking this kind of information into account, it's no secret that work is going to be done but what is it that researchers have been able to find as a result of such work?

Lynda Chin, M.D. - who is not only a professor at the Cancer Genome Atlas but its chair as well - has talked about a series of findings. They came to the surface following a five-year sojourn and I'd like to think that such findings can prove to be useful in time. After all, the information in question referred to factors like genetic mutations, deletions, and others which one would correlate these tumors. It's just a matter of incorporating such information so that therapies can be made with more effectiveness.

It's apparent that other mutations have been discovered in the past, which is something that organizations such as Voices against Brain Cancer will be able to support. Those who have been involved heavily in glioblastoma research can tell you all about the findings, which were referred to in the article. A total of 61 mutated genes were found and the epidermal growth factor receptor has been talked about as well. The EGFR gene is seen as mutated in 57% of tumors, which is an important piece of information.

With so much attention being brought to glioblastoma research in general, it is apparent that these particular tumors are some of the most tremendous you can imagine. To me, these growths have so many intricacies that only those who have been trained in the medical field will be able to effectively pinpoint. However, there seems to be common mutations amongst them. With this in mind, I believe that it is clear that potential for greater therapies being made in the future is a factor that will soon be realized.




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