Monday, November 11, 2013

Cells In Mice Seen By Brain Tumor Research

By Robert Sutter


As you can probably imagine, efforts within the medical field are going to be had in a number of different fashions. Some of them may include the usage of mice, which isn't hard to see why. They react to certain therapies in different ways, which means that the results could most likely play into human usage as well. Brain tumor research is no exception and it seems like there has been some attention brought to human cells in mice recently, which has gone on to earn my attention as well.

Science Daily posted an article about how John Hopkins researchers have been utilizing mice for the sake of testing an FDA-approved drug. It's relevant to brain tumor research because the mice in question had human tumor cells within them. After the administration of such a drug was done, the growth of such tumors have stopped before there was no trace being found as well. It's the kind of story worth focusing on by organizations such as Voices against Brain Cancer, as you could probably imagine.

The story spoke about the IDH1 gene in particular, which was expanded upon back in 2008. This particular gene is seen in 70 to 80 percent of tumors and it is oftentimes mutated. One of the things to take into account is that, with said mutation brought into effect, the brain may not be able to put glucose to use, meaning that the energy typically brought from it cannot be utilized. As you can see, there are challenges to be had in this level of research.

It seems like tumor types are going to shift around in terms of details, whether you realize this to be true or not. After all, keep in mind that there may be many types of growths, some of them obvious more common than others. After all, gliomas are seen as some of the most common, which is arguably why most studies have focused on them more so than any other variant. It's apparent that tumors of all types are going to be looked at within the medical field as well.

I believe that there is a great amount of work to be done in the field of brain tumor research and this story is proof of it. I have to believe that this kind of research is one of the most extensive and all you have to do is look at how complicated these growths are to see it. There's a great amount of success to be had with the trial spoke of in this article. I believe that said success can be transitioned into human use but it's going to take some time.




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